a-PVP

  α-Pyrrolidinopentiophenone (a-PVP), also known as α-pyrrolidinovalerophenone, O-2387, β-keto-prolintane, prolintanone, or desmethylpyrovalerone, is a synthetic stimulant of the cathinone class developed in the 1960s that has been sold as a designer drug and often consumed for recreational reasons. α-PVP is chemically related to pyrovalerone and is the ketone analog of prolintane.

a-PVP acts as a norepinephrine–dopamine reuptake inhibitor (NDRI), similar to methylphenidate and cocaine, with IC₅₀ values of 14.2 and 12.8 nM, respectively, similar to its methylenedioxy derivative MDPV.Similar to other cathinones, α-PVP has been shown to have reinforcing effects in rats.